Reduction+of+Benzofuran-2-yl+Methyl+Ketone+with+Carrot

Philip Deenik

=Synthesis of 1-benzofuran-2-yl-ethanol from benzofuran-2-yl-methyl ketone with carrot=

The reactant of this reaction is benzofuran-2-yl-methyl ketone, the product is 1-benzofuran-2-yl-thhanol, using carrot enzymes.

The Chemistry
Not much is known about how exactly the reduction occures, however it is most likely caused by enzymes in the carrot, as it is quite temperature sensitive. The ketone is reduced to an alcohol by the carrot.

Yield
The atom economy for this reaction (assuming nothing funky happens with the carrot) is 162/178 which is around 91%. However, because of the water in the reaction the effective yield is 162/160, which is around 101.25%.

NFPA
1-benzofuran-2-yl-ethanol: NOT FOUND Health; Fire: Reactivity:

benzofuran-2-yl-methyl ketone: Health: 0 Fire: 0 Reactivity: 0

Equipment and Chemicals needed
This lab will require the following chemicals/biological life forms. benzofuran-2-yl-methyl ketone (20mg) carrot. water TLC paraphernalia pasteur pipette half fill with silica gel hexanes (5 ml will be excess) ethyl acetate

This lab will require the following equipment: carrot peeler

Thanks for submitting this! A bit more detail in the introduction would be helpful.