Chiral+Compounds+and+Green+Chemistry+in+Undergraduate+Organic+Laboratories+Reduction+of+a+Ketone+by+Sodium+Borohydride+and+Bakers+Yeast

Thomas Lewis Chem Lab 243 Carol Higginbothham 4/7/11 Chiral Compounds and Green Chemistry in Undergraduate Organic Laboratories: Reduction Of a Ketone by Sodium Borohydride and Baker’s Yeast Reacants and Products Chrial Compunds of bakers yeast used in a reaction, extracted from its properties using and ethanol in the first part of the experiment to help extract chiral compounds, The second stage of this experiment is to use surcrose and water at 25-30 degrees and the compounds of the bakers yeast to help convert the chiral compounds for the final step of the reaction which involves NaBH4, L-Tartaric Acid, and THF Solvent to Complete the reaction and gain appercation of the green chemistry involed with this chiral compound. Major Concepts The major concepts involed with this experiment is a step in the green chemistry department and involves reduction of a ketone using sodium and also uses chirality to help extract compounds from the baker’s yeast to help obtain what is consider a experiment with less waste that needs to be disposed of properly. Theortical and Effective Masses Effective Mass Yield (%) = Mass of Products x 100 / Mass of Non-Benign Reagents Hazards of Chemicals Sodium Borohydride reagents can produce hydrogen gases and reactions must be properly be kept away from ignition hazards. Tartanic Acid and THF solvent must be handled with care and kept away from the eyes and mouth as well as the NaBH4 Synonym: Sodium tetrahydridoborate CAS Number: [|16940-66-2] Linear Formula: NaBH4 Molecular Weight: 37.83 EC Number: 241-004-4 MDL number: [|MFCD00003518] Synonym: (2//R//,3//R//)-(+)-Tartaric acid, L-Threaric acid CAS Number: [|87-69-4] Linear Formula: HO2CCH(OH)CH(OH)CO2H Molecular Weight: 150.09 Beilstein Registry Number: 1725147 EC Number: 201-766-0 MDL number: [|MFCD00064207] PubChem Substance ID: Synonym: CPME CAS Number: [|5614-37-9] Empirical Formula (Hill Notation): C6H12O Molecular Weight: 100.16 MDL number: [|MFCD08276401] PubChem Substance ID: Equipment Used

Unfortunately this was submitted quite late. Including the reaction, written out, and additional description of hazards would be helpful.